Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity

Pakistan Institute of Medical Sciences60 enrolled

Overview

Type of study: Randomized Clinical trial To compare post-restorative sensitivity between titania nanoparticle reinforced bonding agent and bonding agent without nanoparticles in posterior composite restorations. Participants aged 18 years and above with Class-I and Class-II Carious lesions are allocated in two groups. Group A will undergo composite restoration with Nanoparticles incorporated in bonding agent. Group B will undergo restoration without nanoparticles in bonding agent.

In this study Novel titania nanoparticle reinforced bonding agent will be evaluated for post-restorative sensitivity in composite restorations. Participants following the Inclusion criteria will be allocated in this study by Consecutive non-random sampling technique. Participants will be divided into two groups A and B. After rubber dam isolation, carious lesion will be excavated. In group A, titania nanoparticle reinforced bonding agent will be used for restorative treatment while in group B, Bonding agent without nanoparticles will be used. Post-restorative sensitivity record will be taken at 24 hours, after one week and after one month. Sensitivity will be assessed using Visual analog scale (VAS) mean score.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Carious Lesion

Interventions

Composite resin restoration using Titania nanoparticle reinforced bonding agentPROCEDURE

Each group will receive Composite resin restoration for Class-I and Class-II carious lesion. In group A, titania nanoparticle reinforced bonding agent will be used

Composite resin restoration without Titania nanoparticle incorporated bonding agentPROCEDURE

Composite resin restoration without Titania nanoparticle incorporated bonding agent

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Participants with good general health * Selected teeth should be vital and periodontally healthy * Class-I and II with minimal cavity depth of 3mm, not exceeding 5mm * Defective previous restorations in need of replacement (secondary caries/fractures) * Selected teeth should be in occlusion with natural or prosthetic antagonist and adjacent teeth Exclusion Criteria: * Patients with Temporomandibular disorders * Extremely poor oral hygiene status * Teeth with very deep carious lesions * Teeth with periapical or periodontal pathology * Patients taking anti-inflammatory, analgesics or psychotropic drugs * History of spontaneous pain * Previously root canal treated teeth

Locations (1)

School of Dentistry, Pakistan Institute of Medical Sciences

Islamabad, Pakistan

Outcomes

Primary Outcomes

Post-restorative sensitivity in composite resin restoration

Evaluation of bonding agent with titania nanoparticles and without nanoparticles on post-restorative sensitivity using Visual analog scale with scoring from 0 to 10. Score 10 means worst outcomes

Time frame: 1 month

Data from ClinicalTrials.gov

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