The goal of this observational study is to observe the lung tumor development in lung tumor patients with long-term sleep disorder. The main questions it aims to answer are: * will long-term sleep disorder promote the malignancy of lung tumor * if so, how exactly will the microenvironment of lung tumor change Participants will receive PSQI scale and MRI functional brain imaging before surgery, blood and tumor tissue will be collected during the surgery. Researchers will set non-sleep disorder group as control group to see if lung tumor microenvironment change when long-term sleep disorder exists in lung tumor patiens.
Study Type
OBSERVATIONAL
Enrollment
200
tumor microenvironment in sleep-disordered lung cancer patients
we use single cell sequencing to analyze microenvironment alterations of tumor tissues in enrolled patients.
Time frame: 3 months after surgery
peripheral blood levels of neurotransmitters in sleep-disordered lung cancer patients
peripheral blood levels of epinephrine, noradrenaline, 5-HT in sleep-disordered lung cancer patients
Time frame: 3 months after surgery
Functional brain imaging in sleep-disordered lung cancer patients
Functional brain imaging
Time frame: 3 months after surgery
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