The aim of this study is to evaluate the role of elective bilateral neck dissection in patients with clinically negative lymph nodes (cN0) who underwent salvage total laryngectomy, by estimating the prevalence of histologically positive occult lymph nodes (pN+). Secondary objective will be the assessment of complication rate and the evaluation of 5-year Overall Survival (OS) and 5-year Disease-Specific Survival (DSS) in these patients.
Study Type
OBSERVATIONAL
Enrollment
80
Radical modified type 3 selective bilaterale elective neck dissection
Stefano Settimi
Roma, Italy
Occult lymph node metastasis
Incidence rate of occult lymph node metastasislaryngectomy with clinically negative lymph nodes (cN0), estimating the prevalence of histologically positive lymph nodes (pN+) and predictive factors for cervical lymph nodes metastasis
Time frame: At the time of salvage surgery
Complications of bilateral neck dissection during hospitalization
Complications of bilateral neck dissection during hospitalization
Time frame: Up to 15 days from salvage surgery
Overall survival
Survival of the patient from any disease
Time frame: 5 year
Disease specific survival
Survival of the patient from laryngeal disease
Time frame: 5 years
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