European clinical guidelines do not establish a clear recommendation neither for nor against omentectomy of this segment, the American clinical guidelines recommend omentectomy in view of its potential long-term oncological benefit, and Japanese clinical guidelines only recommend 2nd segment omentectomy in locally advanced gastric cancers (stage T3-T4) recommending omental preservation in early gastric cancers (stage T1-T2). Faced with this lack of consensus, we propose a randomized, prospective and multicentric study in patients with resectable gastric cancer in stage T3-4 N+/- M0. Patients will be randomized into two groups, one where omentectomy of the 2nd omental portion will be performed and another where omental preservation will be performed. The aim of our study is to analyze the disease-free interval and survival between both groups, also comparing postoperative complications and mortality.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
569
Omentectomy vs omental preservations during gastric surgery
disease free interval
time between surgery and recurrence. Units of measure: months
Time frame: 5 years
global survival
survival between surgery and last follow-up date. Units of measure: percentage
Time frame: 5 years
survival at 5 years
survival between surgery and 5 years. Units of measure: percentage
Time frame: 5 years
complications - CCI
type of complications and CCI number. Units of measure: enter number between 1 and 100
Time frame: 30 days after surgery
postoperatory mortality
mortality after surgery. Units of measure: percentage
Time frame: 30 days after surgery
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