Pharmacokinetics of Procaterol in Elite Athletes

Bispebjerg Hospital20 enrolled

Overview

The purpose of the study is to find blood and urine concentrations of procaterol administrated either by inhalation or by tablets in asthmatic and non-asthmatics males. We hypotheis that the concentrations of procaterol in the blood and serum is higher after tablet intake versus inhalation.

Doping study

Study Type

OBSERVATIONAL

Enrollment

Conditions

Asthma

Eligibility

Sex: MALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Doctor diagnosed asthma for the asthmatic group * GINA 1-3 for the asthmatic group * Use of beta2-agonist for at least 12 months for the asthmatic group * age 18-45 * males * informed consent Exclusion Criteria: * smoker or former smoker * airway infection to weeks prior to the study or during the study * other chronic diseaes than asthma and allergy * Use of beta2-agonist 6 days prior to the study * Allergy to the study medicine

Locations (1)

Bispebjerg Hospital

Copenhagen, Denmark

Outcomes

Primary Outcomes

urine concentration of drug 0-24 h

In healthy subjects to investigate drug farmakokenetic

Time frame: 7 days

serum concentration of drug 0-24 h

In healthy subjects to investigate drug farmakokenetic

Time frame: 7 days

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.