The current research is designed to investigate the analgesic efficacy of intravenous ibuprofen on the postoperative analgesic requirements, pain intensity and other recovery parameters.
The patients will be given general anaesthesia. Anaesthesia will be induced by propofol 1-2 mg/kg, and fentanyl 1-2 µg/kg. Endotracheal intubation will be facilitated by atracurium 0.5 mg/kg. Anaesthesia will be maintained by isoflurane in oxygen - air mixture. Transversus abdominis plane block will be performed at the end of the operation. A postoperative analgesic regimen according to group allocation will be started.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
152
800 mg of IV ibuprofen
Faculty of Medicine
Cairo, Shebin Elkom, Egypt
Morphine consumption
mg
Time frame: Postoperative up to 24 hours
Pain intensity
Visual analogue score: a score from 0 to 10( 0= no pain and 10 the worst imaginable pain)
Time frame: Postoperative up to 24 hours
Anaesthesia recovery time
Minutes
Time frame: Perioperative
Duration of post anaesthesia care unit stay
Minutes
Time frame: First postoperative 24 hours
Time of first ambulation
Minutes
Time frame: First postoperative 24 hours
Duration of hospital stay
Days
Time frame: Postoperative up to 4 weeks
Heart rate
Beats/minute
Time frame: Perioperative
Mean arterial blood pressure
mmHg
Time frame: Perioperative
Arterial oxygen saturation
Percentage
Time frame: Perioperative
End tidal carbon dioxide
mmHg
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Time frame: Perioperative
Respiratory rate
Breath/minute
Time frame: Perioperative