The purpose of this study is to evaluate the effectiveness of small phlebotomy tubes to reduce RBC transfusions in medical intensive care unit (ICU) and Intermediate care unit (IMU) patients with low hemoglobin compared with standard size tubes, to compare the intervention and the control groups in regards to: ICU length of stay (LOS), ICU mortality, hospital LOS, and hospital mortality and to assess the acceptability of small phlebotomy tubes in adult ICU and IMU patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
688
In the small tubes group, the recommended blood volumes are 0.5 mL for hematology and single chemistry tests, and 1 mL when multiple chemistry tests are needed. A, a "non-formulary medication" order will be placed in the electronic medical record to alert nurses to collect blood in small tubes. Participants will continue to use small tubes anytime they are in the ICU or IMU.
In the standard tubes group, the recommended blood volumes are 4.0 mL for hematology and 3.0 for chemistry tests.
The University of Texas Health Science Center at Houston
Houston, Texas, United States
RECRUITINGNumber of participants that receive a red blood cell (RBC) transfusion during hospitalization
Time frame: up to 30 days after randomization
Number of RBC units transfused during hospitalization
Time frame: up to 30 days after randomization
Length of stay in ICU
Time frame: completion of study (up to 90 days from enrollment)
Number of participants that died while in ICU
Time frame: completion of study (up to 90 days from enrollment)
Length of stay in hospital
Time frame: completion of study (up to 90 days from enrollment)
Number of participants that died while in hospital
Time frame: completion of study (up to 90 days from enrollment)
Acceptability of small tubes as assessed by determining the number of patients that switch from small tubes to standard tubes
Time frame: up to 30 days after randomization
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