Aortic Stenosis With COmplex PCI (ASCOP) Features Retrospective Registry on Contemporary Management and Outcomes

Niguarda Hospital100 enrolled

Overview

To describe the prevalence and clinical features of patients with severe aortic stenosis undergoing TAVI and concomitant clinically indicated, complex and/or high-risk PCI

The aims of this study are: * to describe the prevalence and clinical features of patients with severe aortic stenosis undergoing TAVI and concomitant clinically indicated, complex and/or high-risk PCI * to depict the different possible strategies that are currently employed in this context and to retrospectively analyze outcomes * to investigate predictors of better outcomes

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Angioplasty, Balloon, Coronary Coronary Artery Disease

Interventions

Transcatheter aortic valve intervention (TAVI) and percutaneous coronary intervention (PCI)PROCEDURE

TAVI and PCI to be administered as per physician's indication and choice, in one or more stages

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

1. Severe, symptomatic aortic stenosis with an indication to TAVI 2. Concomitant, stable CAD with an indication to complex PCI, as anticipated by angiography, defined as follows (one or more features) 1. Left-main (LM) CAD or proximal left anterior descending (LAD) / left circumflex (LCx) lesions requiring LM-PCI 2. Three-vessel disease 3. Last remaining vessel 4. Bifurcation PCI (proximal bifurcation) 5. Severely calcified lesions requiring calcium plaque modification (rotational/orbital atherectomy, intravascular lithotripsy, scoring or cutting balloon) 6. Lesion length \> 30 mm 7. Severely depressed Left ventricular function requiring mechanical circulatory support (intra-aortic balloon pump - IABP, Impella, Extracorporeal Membrane Oxygenation - ECMO

Locations (1)

ASST GOM Niguarda

Milan, Italy

Outcomes

Primary Outcomes

POCE

all-cause deaths, strokes (any), myocardial infarction and major bleedings

Time frame: 1 year

Data from ClinicalTrials.gov

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