A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.

Sohag University100 enrolled

Overview

Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Bone Fracture

Interventions

DexmedetomidineDRUG

(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 5μg Dexametomidine.

KetamineDRUG

(50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 0.1 mg/kg ketamine.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: -The study will include 100 adult patients (18 to 50 years old) with ASA physical status class I and class II undergoing orthopedic lower limb surgeries under itrathecal anathesia . Exclusion Criteria: * Patient refusal. * Drug abuse. * Patient with neurological, psychiatric or neuromuscular disease. * Chronic pain on medicine. * Known allergy to the study medications. * Patients e contraindications to intrathecal anesthesia .

Locations (1)

Sohag University Hospital

Sohag, Egypt

Outcomes

Primary Outcomes

comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery

comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery.

Time frame: 1 year

Central Contacts

zeyad A Ali, Resident

CONTACT

01159596946 zeyadahmed@med.sohag.edu.eg

Ahmed E Abd Elrahman, Professor

CONTACT

Data from ClinicalTrials.gov

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