The main aim of this study is to compare the effect of two non-invasive neuromodulation targets in patients meeting WHO criteria for the post-COVID condition. A randomized, parallel, double-blind study will be conducted. Patients will receive 15 neuromodulation sessions through transcranial electrical stimulation for 3 weeks, associated with cognitive stimulation during therapy. The main objective will be to evaluate the change in physical fatigue. As secondary objectives, changes in cognition, depression, pain, quality of sleep and quality of life will be evaluated. The objective of this study is to evaluate the effect of two targets (left dorsolateral prefrontal and M1) of the neuromodulation intervention, together with cognitive stimulation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
40
Transcranial electrical stimulation over two different brain regions associated with cognitive training. 15 sesions in 3 weeks (5 days/week)
Hospital Clínico San Carlos.
Madrid, Spain
Fatigue Severity Scale (score)
Physical fatigue
Time frame: 1 month
Modified Fatigue Impact Scale (MFIS) (score)
Physical and cognitive fatigue
Time frame: 1 month
FLEI scale (score)
Subjective cognition.
Time frame: 1 month
Beck Depression Inventory (2nd version) (score)
Depressive symptoms
Time frame: 1 month
Pittsburgh Sleep Quality Index (score)
Sleep quality
Time frame: 1 month
Brief Pain Inventory (score)
Pain
Time frame: 1 month
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