The investigators are planning to compare the oxygenation values (Pao2/fio2, lactate etc.) in patients who underwent TCI and inhalation anesthesia in rhinoplasty operation.
Total intravenous anesthesia (TIVA) is a common anesthesia method used today as an alternative to inhalation anesthesia. Loss of consciousness is two important components of general anesthesia, in order to give the patient safe analgesia and not to remember any adverse events related to the operation. While the depth of anesthesia can be controlled by monitoring the minimum alveolar concentration (MAK) in the ventilator devices in the operating room we use modernly, there was no more objective method than measuring the plasma level of drugs in intravenous anesthesia. The schemes created by the anesthetists according to plasma drug levels were used when administering total intravenous anesthesia. Target Controlled Anesthesia (TCI) devices, on the other hand, are pumps that have been used more frequently recently and that can deliver the required blood concentration of a drug in bolus and infusion form according to pharmacokinetics models calculated with personal data. In TCI anesthesia, intravenous infusion of anesthetics provides a more stable drug concentration in the plasma and at the site of action compared to repeated bolus techniques. Thus, it is ensured that the drug remains in the therapeutic range, avoiding the consequences such as over- or under-administration of the drugs. The subject of the study is to determine which of the 2 routinely used methods in rhinoplasty operations affects respiratory functions less.
Study Type
OBSERVATIONAL
Enrollment
106
Patients in the TCI group will be anesthetized with propofol and remifentanil throughout the operation. Patients included in the inhalation anesthesia group will be anesthetized with desflurane and remifentanil with a bispectral index of 40-60 throughout the operation.
Gizem Demir Şenoğlu
Düzce, Düzce, Turkey (Türkiye)
oxygen concentration change throughout the operation
In both general anesthesia methods, blood gas measurements will be made at certain intervals, and pao2 /fio2 in percent (%) ratio will be recorded.
Time frame: 6 periods; 0. basal blood gas(preoperation), 5 min after intubation, 2 hours after intubation, 5 minutes before extubation, 8 hours after extubation
tissue oxygen use as lactate change throughout the operation
In both general anesthesia methods, blood gas measurements will be made at certain intervals serum lactat values mg/dl ratio will be recorded.
Time frame: 6 periods; 0. basal blood gas(preoperation), 5 min after intubation, 2 hours after intubation, 5 minutes before extubation, 8hours after extubation
airway pressures throughout the operation
Airway pressures in cmH2O will be recorded during both anesthesia methods applied throughout the operation.
Time frame: during the operation
lung compliance throughout the operation
The lung compliance in in ml/cmH2O will be recorded during both anesthesia methods applied throughout the operation.
Time frame: during the operation
Nausea
Postoperative nausea, vomiting, recovery time from anesthesia will be recorded.
Time frame: Postoperative 24 hour
vomiting
Postoperative vomiting, recovery time from anesthesia will be recorded.
Time frame: Postoperative 24. hour
recovery time
Postoperative recovery time from anesthesia will be recorded.
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Time frame: Postoperative 24 hour