Study of Peripheral Arterial Disease (PAD) in People With Cancer Who Will Be Having Surgery

N/AActive Not RecruitingNCT05754944

Memorial Sloan Kettering Cancer Center114 enrolled

Overview

Researchers are studying whether people with risk factors for blood circulation disease have a condition called peripheral arterial disease (PAD). People with PAD have poor blood circulation because of narrowing or blocks in blood vessels caused by fat or calcium deposits (atherosclerosis). The study researchers think that PAD may lead to worse outcomes in cancer treatment, but people with cancer are not routinely tested for the disease. The purpose of this study is to find out how common PAD is among people with cancer who have risk factors for blood circulation disease, and to compare how often PAD is diagnosed in different racial groups

Study Type

OBSERVATIONAL

Enrollment

114

Conditions

Peripheral Arterial Disease (PAD) in Cancer Patients

Interventions

ABI/TBIDIAGNOSTIC_TEST

ABI/TBI to be performed after surgery while patient is still admitted at the hospital.

PAD symptoms questionnaire to be administered at baseline before surgery. mLEFS (included in PAD symptoms questionnaire) and WIQ to be administered at baseline before surgery. mLEFS and WIQ will be administered 1 month, 3 months, 6 months after surgery and every 6 months after that for a goal of at least 1 year.

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Cancer patients who are ≥ 65 years old * Either diabetes (on medication or insulin) or smoking history (current smoker, smoking within the last 15 years, ≥ 20 pack years) * Patients who are scheduled for major head and neck, thoracic, abdominal, or pelvic surgery requiring at least a 2-day admission * Ambulatory * ≥ 6 month life expectancy as determined based on clinical judgement by the treating physician. If treating clinician does not confirm life-expectancy ≥ 6 months, will calculate Lee Schoenberg Index using ePrognosis.ucsf.edu. Exclusion Criteria: * Hospice patient, patient with a DNR order * Non-ambulatory, wheelchair/bed bound * \< 6 month life expectancy based on the clinical judgement by the treating physician

Outcomes

Primary Outcomes

prevalence of PAD in cancer patients at high-risk for PAD going to surgery

Completion of ABI/TBI to be able to assess prevalence of PAD

Time frame: 1 year