The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section

Bakirkoy Dr. Sadi Konuk Research and Training Hospital150 enrolled

Overview

The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section under spinal anesthesia. The main question\[s\] it aims to answer are: \[Is transversalis fascia plane block more effective in postoperative analgesia? \] \[Is there a difference between the duration of postoperative first analgesia requirement? \] Since the pain scores after the block at the end of the operation will be evaluated during the postoperative 24 hours, the participants will be asked to give a value between 0 and 10 in certain time periods.

This prospective, randomized trial was conducted at Başakşehir Çam and Sakura City Hospital by the Declaration of Helsinki. After ethics committee approval (decision no: 2022-74, date: 09.03.2022) and written informed consent was obtained from all patients, the trial was conduct-ed according to Consolidated Standards of Reporting Trials (CONSORT) guidelines.A total of 150 patients were divided into two groups: transversal fascia plane block (TFPB group) and Transversus abdominis plane block (TAPB group).VAS values, time to first analgesic requirement, analgesic requirements, nausea \& vomiting and pruritus were evaluated for 24 hours postoperatively (6th hour (T2), 12th hour (T3), 24th hour .

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

150

Conditions

Anesthesia; Sexual

Interventions

Patients undergoing transversalis fascia plane blockPROCEDURE

The investigators applied a transversalis fascia plane block to the group of patients who had a cesarean section under spinal anesthesia to prevent postoperative pain.

Patients undergoing transversus abdominis plane blockPROCEDURE

The investigators applied a transversus abdominis plane block to the group of patients who had a cesarean section under spinal anesthesia to prevent postoperative pain.

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 20-50 years old pregnant woman * ASAII-III * Patients accepting spinal anesthesia Exclusion Criteria: * Morbid obesity(BMI \>40) * Patients who are switched to general anesthesia in an unexpected perioperative situation * Patients with placental anomaly * Patients with bupivacaine allergy * Fetal distress situations too urgent to wait for spinal anesthesia and patients who do not want spinal anesthesia

Outcomes

Primary Outcomes

time of first analgesic need

Our primary goal was to meet the initial analgesic requirement times.

Time frame: 24 hours postoperatively

Secondary Outcomes

visuel analog scale

Our secondary aim was to compare postoperative pain scores. The first 24 hours postoperatively were evaluated.Visual analog scale(VAS) was used to assess postoperative pain.6th, 12th, 24th hour VAS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable.