Crohn's disease is a inflammatory bowel disease evolving towards the destruction of the intestinal wall resulting in stenosing or perforating complications (fistulas, abscesses). The treatment of perforating Crohn's disease is not codified.
The old dogmas leading to surgery after failure of medical treatment have recently been overturned, particularly since the advent of anti-TNFs. Biotherapies now have a central place, including for complicated forms. Previous studies have already looked at the usefulness of anti-TNFs in stenosing forms, or concerning ano-perineal lesions, but what about digestive fistulas. Indeed, data are scarce, especially in paediatrics.
Study Type
OBSERVATIONAL
Enrollment
40
Drug
Surgery
No fistula
Complete remission = clinical remission and biological remission and iconographic remission: * clinical remission (asymptomatic at 12 months from inclusion). * biological remission (normalization of biological parameters 12 months after inclusion). * iconographic remission (no active lesion, and in particular no visualized fistula)
Time frame: 12 month
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