The purpose of this study is to evaluate if BrainPhyt, a microalgae based ingredient may affect cognitive function parameters in older healthy individuals with evidence of age-related cognitive decline. In a double blind, randomized manner, 40 free living males and females between 55 to 75 years with age-associated memory decline will ingest Brainphyt supplement or Placebo for 12 weeks. Cognitive function battery will be realized after 4 and 12 weeks of supplementation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
40
Participants will take BrainPhyt capsules during 3 months
Participants will take placebo capsules during 3 months
Exercise & Sport Nutrition Lab
College Station, Texas, United States
Change in spatial Working Memory
Mean Span Score in Corsi Blocks module of the COMPASS
Time frame: From week 0 to week 12
Change in spatial working memory
Mean Span Score in Corsi Blocks module of the COMPASS
Time frame: From week 0 to week 4
Change in attention and vigilance
Mean reaction time and accuracy in Digit Vigilance Task module of the COMPASS
Time frame: From week 0 to week 12
Change in attention and vigilance
Mean reaction time and accuracy in Digit Vigilance Task module of the COMPASS
Time frame: From week 0 to week 4
Change in executive function
Mean reaction time and accuracy in Stroop task module of the COMPASS
Time frame: From week 0 to week 12
Change in executive function
Mean reaction time and accuracy in Stroop task module of the COMPASS
Time frame: From week 0 to week 4
Change in episodic memory
Mean reaction time and accuracy in Stroop task module of the COMPASS
Time frame: From week 0 to week 12
Change in episodic memory
Mean reaction time and accuracy in Stroop task module of the COMPASS
Time frame: From week 0 to week 4
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Change in perceptual and cognitive skills
Mean reaction time and accuracy in Neurotracker light reaction test
Time frame: From week 0 to week 4
Change in perceptual and cognitive skills
Mean reaction time and accuracy in Neurotracker light reaction test
Time frame: From week 0 to week 12
Stress level
Change in Cohen's Perceived Stress Scale from 0 to 40 (high stress)
Time frame: From week 0 to week 4
Stress level
Change in Cohen's Perceived Stress Scale from 0 to 40 (high stress)
Time frame: From week 0 to week 12
Sleep quality
Change in Leeds Sleep Evaluation questionnaire from 0 to 10 (low sleep quality)
Time frame: From week 0 to week 12
Sleep quality
Change in Leeds Sleep Evaluation questionnaire from 0 to 10 (low sleep quality)
Time frame: From week 0 to week 4
Mood state
Change Bond-Lader Mood rating scale from 0 to 10 (low mood state)
Time frame: From week 0 to week 4
Mood state
Change Bond-Lader Mood rating scale from 0 to 10 (low mood state)
Time frame: From week 0 to week 12
Inflammation IL-6
Change Interleukin-6 level (pg/ml)
Time frame: from week 0 to week 12
Inflammation IL-6
Change Interleukin-6 level (pg/ml)
Time frame: from week 0 to week 4