The purpose of this investigation is to examine the effects of consuming a new dietary microalgae based supplement vs. placebo on neuromuscular function, energy utilization, soreness, perceptual wellness, swelling, and markers of muscle damage and inflammation in healthy young men before and after an acute exercise-induced muscle damage protocol (downhill running), and influence on endurance capacity after prolonged consumption.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
80
University of Central Florida
Orlando, Florida, United States
Neuromuscular function
isokinetic peak torque in Newton per meter (N/m)
Time frame: From 0 to week 4
Energy utilization (Oxygen consumption - VO2)
Running economy during a 5-minute run at 80% of the speed at VO2max with gaz exchange analyzis
Time frame: From 0 to week 4
Energy utilization (Oxygen consumption - VO2)
Running economy during a 5-minute run at 80% of the speed at VO2max with gaz exchange analyzis
Time frame: From 0 to week 8
Isokinetic neuromuscular function
peak torque in Newton per meter (N/m)
Time frame: From 0 to week 8
Isometric neuromuscular function
peak torque in Newton per meter (N/m)
Time frame: From 0 to week 8
Endurance capacity
Maximal oxygen consumption (VO2max) determined during graded exercise test
Time frame: From 0 to week 4
Endurance capacity
Maximal oxygen consumption (VO2max) determined during graded exercise test
Time frame: From 0 to week 8
Soreness and perceptual wellness
Evaluated using using a 100-point numerical pain rating scale anchored with 0= no pain to 100= the most intense pain sensation imaginable after exercise-induced muscle damage protocol
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Time frame: From 0 to week 4
Soreness and perceptual wellness
Evaluated using using a 100-point numerical pain rating scale anchored with 0= no pain to 100= the most intense pain sensation imaginable after exercise-induced muscle damage protocol
Time frame: From 0 to week 8
Swelling - Muscle thickness (mm or cm)
Evaluated using musculoskeletal ultrasound
Time frame: From 0 to week 4
Swelling - overall thigh circumference (mm or cm)
Evaluated using musculoskeletal ultrasound
Time frame: From 0 to week 4
Creatine kinase (UI/I)
Blood marker analyzis
Time frame: After 4 weeks of supplementation
lactate dehydrogenase (U/L)
Blood marker analyzis
Time frame: After 4 weeks of supplementation
Myoglobin (ug/l)
Blood marker analyzis
Time frame: After 4 weeks of supplementation
Interleukin-6 (pg/ml)
Blood marker analyzis - inflammation
Time frame: After 4 weeks of supplementation
Tumor necrosis factor-α (ug/ml)
Blood marker analyzis - inflammation
Time frame: After 4 weeks of supplementation
C-reactive protein (mg/l)
Blood marker analyzis - inflammation
Time frame: After 4 weeks of supplementation
Isometric Neuromuscular function
Peak torque in Newton per meter (N/m)
Time frame: From 0 to week 4