A single center, randomized controlled trial was conducted to investigate whether individualized exercise guidance was more effective in improving pregnancy outcomes in normal pregnant women. What's more, the trial was also conducted to find out whether there is a mediating effect between prenatal exercise and pregnancy outcomes.
Fetal macrosomia refers to newborns with a birth weight more than 4000 grams, which poses varying degrees of risks to the health of both mother and infant and also affects the health outcomes of future generations. Research has found that exercise can effectively reduce the incidence of macrosomia and prevent gestational diabetes mellitus, pregnancy-induced hypertension, and excessive weight gain during pregnancy. However, every pregnant woman's individual situation and exercise habits are different, and personalized guidance based on their own circumstances is necessary during pregnancy exercise. The use of intelligent devices for supervision and management is also essential. To explore the impact of personalized exercise guidance during pregnancy on macrosomia, as well as the mediating effect of weight gain during pregnancy on exercise and macrosomia, we conducted a prospective randomized controlled clinical trial. The study included pregnant women who were over 20 years old, married, singleton, in the mid-term of pregnancy, and had no contraindications for exercise during pregnancy. They were randomly divided into an individualized exercise guidance group and standard clinic prenatal care group. Both groups received routine prenatal care and did not have any special dietary recommendations. The pregnant women in the individualized exercise guidance group received regular exercise guidance from a professional teacher and were supervised and managed through a WeChat group. The main outcome indicators were the incidence of macrosomia and the total weight gain during pregnancy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
326
Participants accept individualized exercise guidance. They are also managed continuously through WeChat group chat during prenatal clinical interval.
Department of ob gyn, Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
macrosomia
Neonatal birthweight is more than 4000 grams.
Time frame: From date of enrollment until the date of delivery, assessed up to 28 weeks.
gestation weight gain（GWG）
Weight before delivery minus weight before pregnancy.
Time frame: From date of enrollment until the date of delivery, assessed up to 28 weeks.
postpartum weight retention（PPWR）
Weight at a certain point after delivery minus weight before pregnancy.
Time frame: From date of enrollment until the date of 42 days postpartum, assessed up to 34 weeks.
diastasis recti abdominis（RDA）
The separation of the left and right rectus abdominis.
Time frame: From date of enrollment until the date of 42 days postpartum, assessed up to 34 weeks.
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