Evaluate the application of the new therapeutic model post Fast Track surgery, in complicated acute appendicitis, in pediatric population on the rate of complications postoperative in the form of abdominal abscesses.
Complicated appendicitis is defined as the finding in the intraoperative study of a perforated, gangrenous or contaminated appendix with the presence of periappendicular abscess. In November 2005, the synthesis of an "Evidence-based clinical practice guide for acute appendicitis in pediatrics" at the Hospital Vall d'Hebron, the result of a committee of experts in the field. This protocol has been the guideline for our center in recent years. Currently, the therapeutic approach is based on monotherapy antibiotic management (except for drug allergies, appendicular peritonitis, immunosuppression or nosocomial acquisition) in the postoperative period, with a minimum duration of 5 days (intravenous treatment). Therefore, the minimum hospital stay in these patients is expected to be equal to or more than 5 days. Acute appendicitis represents the most frequent cause of acute abdomen in pediatric patients older than two years. It affects approximately 80,000 children in the European Union, making appendectomy one of the most frequent non-elective pediatric interventions performed by pediatric surgeons. In recent years, several ambispective studies have been carried out at national level applying new therapeutic models that allow shortening the hospital stay by applying more lax discharge criteria and reducing the duration of intravenous antibiotic treatment, without significant alterations in the rate of postoperative complications. By reducing hospital stay, the fast-track model not only brings clinical benefits to patients, but also economic benefits to the healthcare system.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
158
Amoxicillin clavulanic acid IV 5 days during hospitalization. Application of discharge criteria at 5 postoperative days, according to guidelines current clinic.
Amoxicillin clavulanic acid IV 3 days during hospitalization and at discharge Amoxicillin clavulanic acid PO until day 5. Application of discharge criteria at 72 postoperative hours, administering oral antibiotic therapy with a spectrum similar to that of the control group total of 5 days and sending the patient home with oral analgesia.
Hospital Germans Trias i Pujol
Badalona, Spain
RECRUITINGHospital de la Santa Creu i Sant Pau
Barcelona, Spain
RECRUITINGHospital del Mar
Barcelona, Spain
Postoperative Complication Rate
Time frame: 30 days
Hospital readmission rate
Time frame: 30 days
Procalcitonina value
Blood sample
Time frame: 3 days
Antibiotic consumption
Time frame: 30 days
Associated costs
Time frame: 30 days
Quality of life measure
Measured by EQ-5D-5L questionnaire
Time frame: 30 days
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Hospital Sant Joan de Deu
Esplugues de Llobregat, Spain
RECRUITINGHospital Universitario Dr. Josep Trueta
Girona, Spain
RECRUITINGComplejo Universitario Hospitalario de Santiago de Compostela
Santiago de Compostela, Spain
RECRUITINGHospital Joan XXIII
Tarragona, Spain
NOT_YET_RECRUITING