Efficacy and Safety of Autologous Cryopreserved Platelets in Patients With PTR

Inclusion Criteria: * Patients with ALL，AML，MDS, CML,CLL that suffered from PTR before, with or without HLA antibodies * The platelet level \>150\*10E9/L when considering autologous PLT collection * Age less than 70 years * The expected life more than 3 months * Agree to receive autologous platelet cryopreservation and infusion treatment, and sign the informed consent form Exclusion Criteria: * Blast cells are found in peripheral blood or bone marrow * Patients with bacteremia or sepsis * Coagulation function abnormality * Patients who have a history of thrombosis and are receiving anticoagulant treatment * Severe bleeding within 2 weeks * Participate in another clinical study within 1 month, and have treatment with potential impact on platelets * Patients with mental disease