Within the Denali study the effect of 3 weeks intervention with GOS on the abundance of Bifidobacterium in faecal samples will be investigated.
This randomized, parallel, double-blinded intervention study of 6 weeks will include 88 females, who will consume GOS for three consecutive weeks. Faecal samples will be collected at several time points to measure microbiota composition.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
88
Wageningen University & Research
Wageningen, Gelderland, Netherlands
faecal abundance of Bifidobacterium
faecal abundance of Bifidobacterium.
Time frame: At week -3 (start control)
faecal abundance of Bifidobacterium
faecal abundance of Bifidobacterium.
Time frame: At week 0 (end control)
faecal abundance of Bifidobacterium
faecal abundance of Bifidobacterium.
Time frame: At week 3 (end intervention)
Faecal microbiota composition
Gene-based microbiota profiling of faecal samples
Time frame: At week -3 (start control)
Faecal microbiota composition
Gene-based microbiota profiling of faecal samples
Time frame: At week 0 (end control)
Faecal microbiota composition
Gene-based microbiota profiling of faecal samples
Time frame: At week 3 (end intervention)
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