Early rehabilitation is feasible for stroke patients is still under debate. In addition, IA thrombectomy has been a new treatment for the past few years and currently no known research exploring the efficacy of very early rehabilitation after thrombectomy, or any possible rehabilitation-related adverse effects. Therefore, in this study, the investigators will investigate the effectiveness of earlier rehabilitation intervention after IA thrombectomy for cerebral large vessel occlusion based on functional independence.
The study will be the prospective randomized controlled trial, where patients eligible for inclusion will be randomly assigned to earlier rehabilitation group or control group. The investigators will analyze the correlation between frequency/intensity of rehabilitation and primary/secondary outcomes. Dose-response analysis for earlier rehabilitation will be performed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
exercise group: first bed exercise after 0\~24hr onset ; sit at bed after 24\~48hr onset control group: first bed exercise after 24\~48hr onset ; sit at bed after 48\~72hr onset
National Taiwan University Hospital Hsin-Chu Branch Hsinchu, Taiwan
Hsinchu, Taiwan
RECRUITINGModified Rankin Scale (mRS)
Modified Rankin Scale (mRS) at 3rd months after stroke:6 grades(higher grades means more disability)
Time frame: 3rd months after stroke
Barthel Index
sum score:0\~100(higher score means more functional independence )
Time frame: 1st and 3rd months after stroke
Modified Rankin Scale (mRS)
Modified Rankin Scale (mRS) at 3rd months after stroke:6 grades(higher grades means
Time frame: 1st months after stroke
Fugl-Meyer Assessment
U/E total score:66 L/E total score:34 the higher score means better movement performance
Time frame: 1st and 3rd month after stroke
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