The goal of this observational study is to improve quality of life in sinus node dysfunction patients by utilizing allometric lower rate pacing (or called personalized lower rate, PLR) in standard commercially available dual-chamber pacemakers. The primary objective is to achieve a significant improvement in patients' quality of life with use of PLR pacing in comparison with the control group with nominal lower rate in patients with implanted dual-chamber pacemaker. The secondary objectives are to assess cardiac functional changes in echocardiography of ventricular mechanical performance with a PLR pacing in comparison with the control group with nominal lower rate, and to assess the viability of using elevated blood pressure as a marker for undetected bradycardia and providing allometric rate to correct bradycardia-related increase in arterial systolic blood pressure.
Study Type
OBSERVATIONAL
Enrollment
73
Pacemaker lower rate is set by physician and may be adjusted according to the physician diagnosis.
Shanxi Cardiovascular Hospital
Taiyuan, Shanxi, China
West China Hospital
Chengdu, Sichuan, China
The First People's Hospital of Yunnan Province
Kunming, Yunnan, China
Life quality measurement
SF-36 questionnaire score will be used as the criteria.
Time frame: Within three months after the surgery
Cardiac functional changes
LVEF will be measured
Time frame: Within three months after the surgery
To assess the correlation of elevated blood pressure and bradycardia.
24 hour ambulatory blood pressure will be measured.
Time frame: Within three months after the surgery
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