Kerecis Fish Skin Grafts With and Without Platelet Rich Plasma (PRP)

Inclusion Criteria: * Patient is over the age of 18 years; * The targeted wound is deemed a chronic, nonhealing wound after six weeks of treatment; - - Patient of Dr. Eldridge, Dr. Glenn, or Dr. Worley; * Target wound size must be between 2 cm x 2 cm x 0.1 cm deep and 10 cm x 10 cm x 5 cm deep; * Surgical candidate for standard of care Kerecis® xenograft surgery. Exclusion Criteria: * Patient with hemoglobin values less than 6.9 g/dL drawn at least 30 days prior to the Kerecis® xenograft surgery; * Patient with a known allergy or other sensitivity to fish material; * Patient is currently undergoing chemotherapy or radiation therapy; * The targeted wound is of autoimmune origin; and Non-English-speaking patients.