Study of Brain Anatomo-functional Substrates Related to the Use of Human Tool by Means of Simultaneous Acquisition of Magnetic Resonance Imaging and Electroencephalogram

IRCCS SYNLAB SDN100 enrolled

Overview

This is an observational study, conducted on subjects with neurological disorders primarily involving the frontal and parietal lobes of the brain. Throughout the indicated period, the study will aim to enroll 100 subjects divided into 30 units per year. Specifically, the study will be carried out on patients with fronto-parietal dysfunction for whom a prescribed a clinical investigation of electroencephalogram and MRI

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Patients With Frontal and Parietal Lobe Dysfunction

Interventions

electroencephalogram (EEG) and magnetic resonance (MR)COMBINATION_PRODUCT

High-resolution 3D T1 and T2 sequences, acquired in the sagittal plane and MR reconstructed in the remaining orthogonal planes, for morphological assessment of different cortical and subcortical. EEG tracing involving recording channels such as eye tracking (eye-tracking: electrooculogram, pupillometry, saccades, fixation times on areas predefined areas), performance measures (response times), electrocardiogram and electromyogram proper to clinical acquisition

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * subjects of either sex with fronto-parietal dysfunction, who are able to able to provide voluntary consent, who have been asked for clinical purposes for an EEG and an MRI Exclusion Criteria: * pregnant or presumed pregnant subjects and subjects with claustrophobia or with contraindications to the examination.

Outcomes

Primary Outcomes

Combination of EEG and functional MR (fMRI)

Interception of differences during simultaneous acquisition related to the variation of action readiness (action readiness) suggested by the visual-perceptual context

Time frame: 1-36 months