Brachial plexus block is used for upper limb surgery. Local anesthesia alone for brachial plexus block provides good operative conditions, but have short duration of postoperative analgesia. Hence, various adjuvants to local anaesthetic agents to prolong the duration of peripheral nerve, analgesia. However, results are either inconclusive or associated with side effects. The purpose of this study is to determine whether dexmedetomidine as an adjuvant to ropivacaine in brachial plexus block improve quality of block in terms of duration of post operative analgesia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Group R includes 0.35% ropivacaine 20ml, 1.5 % lidocaine with adrenaline 10ml
Dexmedetomidine 1mcg/kg and 0.35% ropivacaine with normal saline (20ml), 1.5% lidocaine with adrenaline (10ml) in group RD
Nepal medical college
Kathmandu, Bagmati, Nepal
Assess the duration of analgesia after brachial plexus block with ropivacaine and dexmedetomidine
Analgesia will be assessed with the help of Visual analogue score ( VAS). VAS greater than 3 will be given inj.ketorolac 30mg IV.
Time frame: 5 months
Assess the onset of sensory and motor block after brachial plexus block with ropivacaine and dexmedetomidine
Sensory block assessed by 3point scale 0 normal sensation 1. loss of sensation of pinprick 2. loss of sensation of touch Duration of sensory block, defined as time interval between complete sensory block and complete resolution of anesthesia (score 0).Motor blockade assessed by modified Bromage scale (MBS) 0-able to raise extended arm to 90 degree for full two seconds 1. able to flex elbow, move fingers but unable to raise extended arm 2. unable to flex elbow but able to move fingers 3. unable to move arm, elbow, fingers Duration of motor block defined as time interval from complete motor block to recovery of complete motor function (MBS 0).
Time frame: 5 months
Assess the duration of sensory and motor block after brachial plexus block with ropivacaine and dexmedetomidine
Duration of sensory block, defined as time interval between complete sensory block and complete resolution of anesthesia (score 0). Duration of motor block defined as time interval from complete motor block to recovery of complete motor function (MBS 0).
Time frame: 5months
Assess any complications of study drugs
Complications like bradycardia assessed by continue ECG monitoring, Hypotension will be assessed by NIBP
Time frame: 5 months
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