This study will test whether minoxidil taken by mouth (oral minoxidil) can improve hair loss caused by cancer treatment in children and young adults. In addition, the researchers will test the safety of oral minoxidil, and see if the study drug causes few or mild side effects in participants. Other purposes of this study include looking at whether participants are able to follow their study drug dosing schedules, and how oral minoxidil affects participants' quality of life.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
10
minoxidil at a dose of 0.01 (\<40kg) and 0.02 (≥40kg) mg/kg/day
placebo for 4 months
Memorial Sloan Kettering Cancer Center
New York, New York, United States
change in the target area (1/3 of the distance midline from glabella to occiput from the front toward the back) hair density
as assessed by Hairmetrix allows trichoscopy (dermoscopic imaging of the scalp and hair) in real time. It requires no special scalp or hair preparation and allows fully automated unclipped analysis, producing measurements.
Time frame: at 4 months
change in the target area (1/3 of the distance midline from glabella to occiput from the front toward the back) hair density
as assessed by Hairmetrix allows trichoscopy (dermoscopic imaging of the scalp and hair) in real time. It requires no special scalp or hair preparation and allows fully automated unclipped analysis, producing measurements.
Time frame: at 8 months
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