Maca in Healthy Subjects After Strenuous Endurance Exercise

Taipei Medical University50 enrolled

Overview

The aim of this study is to investigate Lepidium meyenii (Maca) extract supplementation on exercise-induced responses of the biochemical, and physiological parameters.

Thirty healthy male participants were divided into Maca group (2.25 g of Maca extract, twice per day for 12 weeks) and placebo group (n = 15). All participants conducted a graded exercise test on treadmill to determine the maximal oxygen consumption (VO2max) before and after supplementation, and the speed equivalent to 70% VO2max was conducted for an exhaustive endurance exercise test by treadmill for 1 hours, followed by 90% VO2max until exhaustion.The time to exhaustion, peak oxygen consumption, maximal heart rate and average heart rate will be recorded during the exercise period. Venous blood samples will be drawn before, immediately after, 2-hour after, 4-hour after, and 24-hour after the exhaustive endurance exercise test. Data was analyzed by Two-way mixed design ANOVA.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Healthy

Interventions

macaDIETARY_SUPPLEMENT

2.25 g of Maca extract, twice per day for 12 weeks

placeboDIETARY_SUPPLEMENT

2.25 g of starch, twice per day for 12 weeks

Eligibility

Sex: MALEMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- The volunteers included have conditions as stated below : 1. male adult whose no history of cardiovascular, liver, kidney and diabetes disease 2. no acute sport injury 3. did not participated in any clinical trials or research in the last 3 months before our experiment 4. no supplements were taken during the experimental period 5. were requested to maintain their regular daily life style and avoid alcohol intake Exclusion Criteria: \- The volunteers were excluded if they have the situation stated below: 1. history of cardiovascular, liver, kidney and diabetes disease 2. acute sport injury 3. participated in any clinical trials or experimental research in the last 3 months before our experiment 4. taking supplement during the experimental period 5. did not maintain their regular eating habit or drink alcohol

Locations (1)

Taipei Medical University

Taipei, Taiwan

Outcomes

Primary Outcomes

Concentration of leukocyte

Time frame: before exercise

Concentration of leukocyte

Time frame: immediately after exercise

Concentration of leukocyte

Time frame: 2-hour after exercise

Concentration of leukocyte

Time frame: 4-hour after exercise

Concentration of leukocyte

Time frame: 24-hour after exercise

Concentration of neutrophil

Time frame: before exercise

Concentration of neutrophil

Time frame: immediately after exercise

Concentration of neutrophil

Time frame: 2-hour after exercise

Concentration of neutrophil

Time frame: 4-hour after exercise

Concentration of neutrophil

Time frame: 24-hour after exercise

Concentration of lymphocyte

Time frame: beore exercise

Concentration of lymphocyte

Time frame: immediately after exercise

Concentration of lymphocyte

Time frame: 2-hour after exercise

Data from ClinicalTrials.gov

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