This study evaluates whether plaques in young patients with familial hypercholesterolemia (aged below 50 years) are susceptible to significant plaque regression with early, intensive lipid lowering therapy.
Study Type
OBSERVATIONAL
Enrollment
60
Amsterdam UMC, location AMC
Amsterdam, North Holland, Netherlands
RECRUITINGCAD Progression
Difference in total plaque volume between the initial and follow-up CCTA scan
Time frame: 40 Weeks
Non-calcified plaque progression
Difference in non-calcified plaque volume between the baseline and follow-up CCTA scan
Time frame: 40 Weeks
Calcified plaque progression
Difference in calcified plaque volume between the baseline and follow-up CCTA scan
Time frame: 40 Weeks
Number of high-risk plaques
Difference in number of high-risk plaques between the baseline and follow-up CCTA scan
Time frame: 40 Weeks
Difference in Pericoronary Adipose Tissue Attenuation
Difference in Pericoronary Adipose Tissue Attenuation between the baseline and follow-up CCTA scan
Time frame: 40 Weeks
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