Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy

Alexandria University26 enrolled

Overview

The aim of this study was to evaluate the effect of hyaluronic acid gel after photobiomodulation on the healing of surgical gingivectomy sites

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Gingival Enlargement

Interventions

PhotobiomodulationDEVICE

The surgical sites were irradiated with a diode laser (980 nm, 0.2W) only.

Hyaluronic acid after photobiomodulationOTHER

The surgical sites after gingivectomy were irradiated with a diode laser (980 nm, 0.2W) then covered by 2% Hyaluronic acid gel loaded in a special appliance for each patient.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Chronic inflammatory gingival enlargement grade 2 and 3 according to the gingival overgrowth index by Miller and Damn. * Adequate amount of keratinized tissue. * Attachment loss= 0 * Well educated patients as post-operative instructions need to be followed precisely. Exclusion Criteria: * Patients with history of smoking * Pregnant women * Patients with bad oral hygiene * Patients who have any known systemic disease that interfere with performance of surgical gingivectomy or periodontal wound healing * Patients who have any previous adverse reactions to the products (or similar products) used in this study

Locations (1)

Faculty of Dentistry, Alexandria University

Alexandria, Egypt

Outcomes

Primary Outcomes

Wound healing

Assessed using Landry's healing index which grades the wound on a scale of 1 (poor) to 5 (excellent) * Very poor (1): ≥50% of gingiva red, bleeding on palpation, Granulation tissue present, Non-epithelialized incision margin with loss of epithelium beyond the margin. * Poor (2): ≥50% of gingiva red, bleeding on palpation, Granulation tissue present, Non-epithelialized incision margin with exposed connective tissue * Good (3): ≥25% and\<50% of gingiva red, No bleeding on palpation, no granulation tissue, No exposed connective tissue on the incision margin * Very good (4): \<25% of gingiva red, No bleeding on palpation, no granulation tissue, No exposed connective tissue on the incision margin * Excellent (5): All tissues are pink, No bleeding on palpation, no granulation tissue, No exposed connective tissue on the incision margin

Time frame: up to 21 days

Perceived pain

This was assessed using Visual Analogue Scale (VAS). Patients were instructed to chart their perceptions of pain using VAS ranging from 0-10; where 0 represents no pain/burning sensation and 10 represents severe pain/burning sensation.

Time frame: up to 21 days

Data from ClinicalTrials.gov

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