The purpose of this observational study is to evaluate patients who are planning to administer sugammadex after rocuronium or vecuronium is used. The main questions it aims to answer are: 1. Prescription pattern of sugammadex 2. Effectiveness and safety of sugammadex Since this study is observational, only data generated under daily treatment are to be collected, and no additional tests or drug administration is conducted for the study. The patients are observed from baseline to 24 hours after the initial administration of sugammadex.
Study Type
OBSERVATIONAL
Enrollment
6,458
As this is a non-interventional study designed to collect data as part of routine clinical practice, the type and dose of neuromuscular blocking agents are all based on the clinician's judgment.
Korea University Anam Hospital
Seoul, Seongbuk-gu, South Korea
Re-administration rate of sugammadex
The number and ratio of patients re-administered with sugammadex within 24 hours of the initial administration of sugammadex are evaluated.
Time frame: baseline~24 hours after administration
Prescription pattern of sugammadex
The ratio of patients is presented for each administered time and dose.
Time frame: baseline~24 hours after administration
Incidence rate of postoperative residual curarization (PORC)(TOFr<0.9)
The TOFr (train-of-four ratio) is measured at 3 and 30 minutes after administration of sugammadex. The number and ratio of patients with a TOFr \<0.9 are defined as PORC(TOFr\<0.9). The TOFr is expressed as a decimal from 0.0 up to 1.0.
Time frame: at 3 and 30 minutes after administration of sugammadex
Incidence rate of postoperative residual curarization (PORC)(TOFr<1.0)
The TOFr (train-of-four ratio) is measured at 3 and 30 minutes after administration of sugammadex. The number and ratio of patients with a TOFr \<1.0 are defined as PORC(TOFr\<1.0). The TOFr is expressed as a decimal from 0.0 up to 1.0.
Time frame: at 3 and 30 minutes after administration of sugammadex
Analysis of clinical factors affecting sugammadex re-administration
The number and ratio of patients who had these clinical factors are evaluated.
Time frame: baseline~24 hours after administration
Incidence rate of respiratory complications related to postoperative residual muscle relaxation after surgery
The number and ratio of patients who had respiratory complications related to postoperative residual muscle relaxation after surgery are evaluated.
Time frame: time from the first administration of sugammadex ~ 24 hours after administration
TOFr before sugammadex administration
The TOFr (train-of-four ratio) is measured before each administration of sugammadex. The TOFr is expressed as a decimal from 0.0 up to 1.0.
Time frame: baseline~24 hours after administration
TOFr before extubation
The TOFr (train-of-four ratio) is measured before extubation. The TOFr is expressed as a decimal from 0.0 up to 1.0.
Time frame: baseline~24 hours after administration
Time to extubation
The time from the first administration of sugammadex or the last administration of NMBA to the time of extubation is measured in minutes.
Time frame: baseline~24 hours after administration
Time surpassed from the expected dismissal time from the recovery room
The time of dismissal from the recovery room is recorded for each patient.
Time frame: baseline~24 hours after administration
Ratio of unplanned transfer to the intensive care unit(excluding lung surgery and heart surgery)
The number and ratio of patients who was moved from the recovery room to the intensive care unit unplanned.
Time frame: time from the first administration of sugammadex ~ 24 hours after administration
Incidence rate of PONV(postoperative nausea and vomiting)
The number and ratio of patients who experiences PONV(postoperative nausea and vomiting).
Time frame: time from the first administration of sugammadex ~ 24 hours after administration
Incidence rate of adverse drug reaction
The number and ratio of patients who experiences adverse drug reactions in which their relationship to sugammadex cannot be ruled out.
Time frame: time from the first administration of sugammadex ~ 24 hours after administration
Incidence rate of serious adverse drug reaction
The number and ratio of patients who experiences serious adverse drug reactions in which their relationship to sugammadex cannot be ruled out.
Time frame: time from the first administration of sugammadex ~ 24 hours after administration
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