To determine whether an integrated AI decision support can save time and improve accuracy of assessment of echocardiograms, the investigators are conducting a blinded, randomized controlled study of AI guided measurements of wall thickness in parasternal long axis view compared to sonographer measurements in preliminary readings of echocardiograms.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
TRIPLE
Enrollment
4,000
A sonographer will assess measurements of left ventricular diameter during diastole (LVIDd), intraventricular septum thickness during diastole (IVSd) and left ventricular posterior wall thickness during diastole (LVPWd).
An AI model will assess measurements of left ventricular diameter during diastole (LVIDd), intraventricular septum thickness during diastole (IVSd) and left ventricular posterior wall thickness during diastole (LVPWd).
Cedars-Sinai Medical Center
Los Angeles, California, United States
Proportion of studies for which the difference in wall thickness between preliminary to overread is greater than 0.3cm for LVIDd
Proportion of significant difference in LVIDd between preliminary to final assessment
Time frame: 10 Minutes
Proportion of studies for which the difference in wall thickness between preliminary to overread is greater than 0.2cm for IVSd
Proportion of significant difference in IVSd between preliminary to final assessment
Time frame: 10 Minutes
Proportion of studies for which the difference in wall thickness between preliminary to overread is greater than 0.2cm for LVPWd
Proportion of significant difference in LVPWd between preliminary to final assessment
Time frame: 10 Minutes
mean absolute error (MAE) of LVIDd between preliminary to overread between the two arms
Measurement difference of LVIDd between preliminary to final assessment
Time frame: 10 Minutes
mean absolute error (MAE) of IVSd between preliminary to overread between the two arms
Measurement difference of IVSd between preliminary to final assessment
Time frame: 10 Minutes
mean absolute error (MAE) of LVPWd between preliminary to overread between the two arms
Measurement difference of LVPWd between preliminary to final assessment
Time frame: 10 Minutes
mean absolute error (MAE) of wall thickness between cardiologist overread vs. historical clinical report wall thickness
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Mean absolute error (MAE) of wall thickness between cardiologist overread with initial interpretation vs. prior clinical report wall thickness
Time frame: 10 Minutes
Time to complete each imaging study
Time for sonographers and cardiologists to complete a study (in seconds)
Time frame: 10 Minutes
Effects of the AI systems integration with computer-human interaction (Blinding)
Whether cardiologists can tell the difference between human vs. AI initial interpretation (Bang's blinding index, or the proportion of studies guessed correctly to be AI or sonographer compared to ground truth of whether it was AI or sonographer).
Time frame: 10 Minutes