This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1015). The goal of this clinical trial is to confirm the concordance rate between intra-operative frozen section pathological diagnosis and post-operative paraffin embedded pathological diagnosis, and use this result to guide surgical treatment for early stage (cT1N0M0) lung adenocarcinomas.
Study Type
OBSERVATIONAL
Enrollment
1,063
Surgical resection of lung adenocarcinoma. Wedge resection, segmentectomy or lobectomy will be performed according to each patients' condition.
Fudan University Cancer Center
Shanghai, Shanghai Municipality, China
RECRUITINGConcordance rate
Concordance rate between intraoperative frozen section and postoperative paraffin embedded pathology in making the diagnosis of IASLC grades of lung adenocarcinoma
Time frame: 2 years
Concordance rate
Concordance rate between intraoperative frozen section and postoperative paraffin embedded pathology in making the diagnosis of lung adenocarcinoma subtypes according to the WHO classifications.
Time frame: 2 years
Concordance rate
Concordance rate between intraoperative frozen section and postoperative paraffin embedded pathology in making the diagnosis of pleural invasion and lymph node invasion.
Time frame: 2 years
Concordance rate
Concordance rate between intraoperative frozen section and postoperative paraffin embedded pathology in making the diagnosis of spread through air space (STAS).
Time frame: 2 years
Recurrence-free survival (RFS)
Recurrence-free survival (RFS) is defined as the time from date of curative surgery to the time of recurrence or death, whichever comes first.
Time frame: 5 years
Overall survival (OS)
Overall survival (OS) is defined as the time from date of curative surgery to the time of death of any reason.
Time frame: 5 years
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