Quality of Recovery From Mastectomy With and Without PECS Blocks

N/AActive Not RecruitingNCT05795413

Endeavor Health800 enrolled

Overview

This is a prospective observational study. Investigators want to understand post-operative recovery for patients undergoing mastectomy at NorthShore University HealthSystem. Some of these patients receive PECS blocks with Liposomal Bupivacaine and some do not receive a block. Investigators want to know whether patients who receive a block have better post operative recovery and pain control than patients who do not receive one. Investigators also want to understand whether PECS blocks with Liposomal Bupivacaine improves quality of recovery at 72 hours post operatively.

Investigators plan to approach and consent 800 patients undergoing mastectomy, 400 with PECS blocks and 400 without. Investigators will assess their quality of recovery using the QoR 15 survey at 72 hours post operatively. In addition, investigators will also record VAS scores immediately postoperatively and at 24, 48, and 72 hours postoperatively. The study team will also calculate the total morphine equivalents (MMEs) required for each patient after 72 hours.

Study Type

OBSERVATIONAL

Enrollment

800

Conditions

Post Operative Pain Quality of Recovery After Mastectomy

Interventions

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Must be female Must be \>18 years old and \< 90 years old Must be able to consent in English or Spanish May or may not have breast cancer (prophylactic mastectomy) Must be undergoing unilateral or bilateral mastectomy of any type May choose to proceed with or without breast reconstruction Exclusion Criteria: Allergy to all narcotic or local anesthetic medications Intake of any chronic opioids or pain medications preoperatively for a chronic condition or chronic use. Subjects who received PECS blocks but whose block failed or is deemed not effective by an anesthesia provider as indicated by postoperative evaluation exam. Vulnerable subjects (children, prisoners, pregnant women)

Outcomes

Primary Outcomes

Quality of Recovery 15 Survey

Patients will complete the quality of recovery 15 survey 72 hours after surgery. This is a scale from 0 to 150. A score of 150 indicates better post operative recovery.

Time frame: 72 hours post operatively

Secondary Outcomes

Visual analog scale

This is a pain scale from zero to ten. A score of 10 indicates worse pain.

Time frame: Immediately post operatively

Visual analog scale

This is a pain scale from zero to ten. A score of 10 indicates worse pain.

Time frame: 24 hours post operatively

Visual analog scale

This is a pain scale from zero to ten. A score of 10 indicates worse pain.

Time frame: 48 hours post operatively

Visual analog scale

This is a pain scale from zero to ten. A score of 10 indicates worse pain.

Time frame: 72 hours post operatively

Morphine milligram equivalents

We will record the amount of pain medication each patient takes after surgery. A higher morphine milligram equivalent indicates a higher amount of opioid medication used.

Time frame: Immediately post operatively

Morphine milligram equivalents

We will record the amount of pain medication each patient takes after surgery. A higher morphine milligram equivalent indicates a higher amount of opioid medication used.

Time frame: 24 hours post operatively

Morphine milligram equivalents

We will record the amount of pain medication each patient takes after surgery. A higher morphine milligram equivalent indicates a higher amount of opioid medication used.

Time frame: 48 hours post operatively

Morphine milligram equivalents

We will record the amount of pain medication each patient takes after surgery. A higher morphine milligram equivalent indicates a higher amount of opioid medication used.

Time frame: 72 hours post operatively

Quality of Recovery From Mastectomy With and Without PECS Blocks

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes