Establishment of a Feasibility Model for NOSE Surgery Based on Machine Learning

N/ANot Yet RecruitingNCT05797064

Sixth Affiliated Hospital, Sun Yat-sen University460 enrolled

Overview

The goal of this observational study is to test in patients with resectable rectosigmoid cancers. The main question it aims to answer is establishment of a feasibility model for predicting natural orifice specimen extraction surgery (NOSES) based on machine learning.

Study Type

OBSERVATIONAL

Enrollment

460

Conditions

Machine Learning Surgery Rectosigmoid Cancer Natural Orifice Specimen Extraction Surgery

Interventions

Natural Orifice Specimen Extraction SurgeryPROCEDURE

Natural Orifice Specimen Extraction Surgery (NOSES) is a minimally invasive surgical technique that aims to reduce the size and number of incisions required during certain surgeries. In NOSES, the surgical specimen (such as a diseased organ or tumor) is removed from the body through a natural orifice (such as the mouth, anus, or vagina), rather than through an incision in the abdominal wall. In this trial, we will extract surgical specimens from the rectum to reduce trauma to the abdominal wall.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients diagnosed with colorectal cancer or large adenoma who are suitable for laparoscopic colorectal surgery; 2. Tumor staging ≤ T3 without invasion of surrounding organs; 3. No abdominal seeding or distant organ metastasis; 4. Clear and complete imaging data (CT, pelvic MRI) that can be processed by a computer; 5. Feasible evaluation and determination for obtaining specimens through the rectal channel during preoperative and intraoperative assessments. Exclusion Criteria: 1. Contraindications for laparoscopic colorectal surgery; 2. Tumor staging is T4, or there are cancer nodules; 3. Presence of metastasis or distant organ metastasis; 4. Incomplete imaging data; 5. Preoperative intestinal obstruction; 6. Tumor or specimen diameter larger than the transverse diameter of the pelvic outlet; 7. Previous rectal radiotherapy; 8. Unsuitable evaluation and determination for obtaining specimens through the rectal channel during preoperative and intraoperative assessments.

Locations (1)

The Sixth Affiliate Hospital of Sun Yat-Sen University

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

The number of successful operations performed

Accuracy will be calculated by the number of successful operations performed

Time frame: 3 years

The number of successful operations actually completed.

Accuracy will be calculated by the number of successful operations actually completed.

Time frame: 3 years

Data from ClinicalTrials.gov

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