The clinical trial studies patients with gingival recession defects (receding gums). The goal of the study is to test whether the additional use of enamel matrix derivatives (EMD), combined with the use of a coronally advance flap (CAF) and a CM (collagen matrix), shows a better outcome compared to a comparison group. The comparison group comprises patients receiving treatment with CAF and CM without the use of EMD.
The study aims to evaluate the influence of the additional use of EMD in treatment of gingival recession defects using a coronally advance flap (CAF) and a CM (collagen matrix) by means of digital and clinical assessment methods. The reference group comprises patients receiving treatment with CAF and CM without the application of EMD. In this prospective, randomized, controlled study, recession height and area, width and thickness of keratinized gingiva, pocket probing depth, and the clinical attachment level were measured at baseline and followed-up for one year. 15 patients with 24 gingival recession defects (Recession Type 1 after Cairo/Miller Class I or II) were recruited and were randomly assigned into the two treatment groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
15
Gingival recession height
Gingival recession height in millimeters, measured as the distance from cementoenamel junction to gingival margin
Time frame: 12 months postoperatively
Width of keratinized tissue (WKT)
Width of keratinized tissue in millimeters, .as distance between gingival margin and muco-gingival junction
Time frame: 12 months postoperatively
pocket probing depth (PPD)
Pocket probing depth in millimeters, measured as the distance from gingival margin to bottom of gingival sulcus
Time frame: 12 months postoperatively
Clinical attachment loss (CAL)
Clinical attachment loss in millimeters
Time frame: 12 months postoperatively
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