ALPHA LONG Study- BioMatrix AlphaTM Stent Study in Patients With CAD

Inclusion Criteria: 1. Patients must provide written informed consent 2. Patient is at least 18 years old 3. Patients scheduled to undergo PCI of a de novo lesion(s) with reference vessel diameter and lesion length suitable for treatment with at least one study device 4. Patients who agree to comply with the follow up requirements 5. Patients with a life expectancy of \> 1 year at time of consent 6. Patients eligible to receive for ≥6 months either dual anti-platelet therapy (DAPT, i.e. 75 mg clopidogrel or another P2Y12 inhibitor per choice of the investigator, and 75-100 mg aspirin) or a combination of an oral anti-coagulant (Vitamin K antagonist or novel anti-coagulant) and a single anti-platelet agent 7. Hemodynamically stable patients Exclusion Criteria: 1. Inability to provide informed consent 2. Currently participating in another clinical trial 3. Planned surgery ≤6 months of PCI unless DAPT or combination anti-thrombotic/anti-platelet therapy is maintained throughout the peri-surgical period 4. Planned use of additional stents other than BioMatrix AlphaTM during the index procedure. 5. Patients with a life expectancy of \< 1 year 6. Known hypersensitivity or contraindication to aspirin, clopidogrel (or to any other P2Y12 inhibitor if applicable), cobalt chromium, zinc, Biolimus A9 or a sensitivity to contrast media, which cannot be adequately pre-medicated