Frontal Alpha Asymmetry and Pediatric Emergence Delirium

Gangnam Severance Hospital80 enrolled

Overview

This study aimed to investigate whether the association between the preoperative anxiety level and emergence delirium involves EEG frontal alpha asymmetry in pediatric patients undergoing ophthalmic surgery under general anesthesia. The investigators hypothesized that EEG frontal alpha asymmetry contributes a significant portion of the preoperative anxiety - emergence delirium association in pediatric patients. Mediation analysis will be performed to estimate the relationships between preoperative anxiety of children (modified Yale Preoperative Anxiety Scale (mYPAS)), EEG frontal alpha asymmetry, and emergence delirium (Pediatric Assessment of Emergence Delirium (PAED) scale).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Emergence Delirium

Interventions

Ophthalmic surgeryPROCEDURE

Ophthalmic surgery will be performed as standard practice of our institution.

Eligibility

Sex: ALLMin age: 2 YearsMax age: 8 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Children aged 2-8 year * Children with an American Society of Anesthesiologists (ASA) physical status of I-II * Children who are scheduled to undergo elective ophthalmological requiring general anesthesia Exclusion Criteria: * Emergency surgery * Patients with developmental delays * Patients with neurological or psychiatric diseases associated with symptoms of agitation, anxiety, attention deficit, sleep disturbances * Patients with autism * Patients with a recent history (within one month) of receiving general anesthesia * Patients with congenital or genetic diseases that may influence brain development

Outcomes

Primary Outcomes

The peak PAED score

The peak PAED score is the primary outcome variable for mediation analysis

Time frame: After the completion of surgery, during the PACU stay. PAED score will be measured every 10 minutes during the PACU stay.