Health Effects of Oat Bioactives (Betaglucan) in Human

Lund University20 enrolled

Overview

Aim of the study is to investigate health effects of oats and oat derived components, in human intervention studies, with the purpose to build new knowledge for development of cardiometabolic protective foods.

The overall goal is to increase the knowledge which can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people. More specifically the primary purpose of this project is to evaluate effects in healthy humans on cardiometabolic test markers of oat and oat based product. The new knowledge will form a base for the development of oat based food products with added health values.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Healthy

Interventions

Effects of Oat and Oat Components on Cardiometabolic risk variablesDIETARY_SUPPLEMENT

Oat and oat bioactive components consumed as breakfast meal.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- Healthy adults BMI 18.5 - 28 Kg/m2 Non smokers Consuming a non-vegetarian diet that follows the Nordic diet recommendation. Exclusion Criteria: \- Fasting blood glucose concentration \>6.1 mmol/l Known cardio-metabolic disease (e.g. diabetes, hypertension, metabolic syndrome). Gastro-intestinal disorders such as IBS (irritable bowel syndrome) that can interfere with the study results, food allergies. No antibiotics or probiotics should have been consumed within 4 weeks prior to and during the study.

Locations (1)

Food Technology, engineering and Nutrition, LTH, Lund University

Lund, Skåne County, Sweden

Outcomes

Primary Outcomes

Blood glucose regulation

Postprandial blood glucose regulation (incremental area under the curve) acute after intake of the test products and at forthcoming meals within 5.5 hours after consumption of test products.

Time frame: Time Frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)

Secondary Outcomes

Serum insulin

Acute effects of postprandial serum insulin concentrations (incremental area under the curve) after intake of the test products.

Time frame: Time Frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)

Data from ClinicalTrials.gov

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