Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Inclusion Criteria: 1. Age 50-75 years old, gender unlimited; 2. Diagnosed as coronary atherosclerotic heart disease 3. The informed consent for the study has been signed Exclusion Criteria: 1. Those who are unable to cooperate with the examination; 2. Poor imaging quality of refractive interstitial opacity; 3. Macular edema or complicated with macular membrane and senile macular degeneration; 4. Have a history of previous fundus surgery; 5. Those with eye diseases that can cause changes in the microvessels of the fundus; 6. Abnormal elevated intraocular pressure; 7. Moderate or above refractive error (≥ ± 3 diopters) 8. People with cognitive impairment, material dependence, and serious mental illness; 9. Those who do not cooperate with follow-up; 10. Those who participate in other clinical trials at the same time