Rehabilitation in Parkinson Disease Cyclone in Life

IRCCS Centro Neurolesi Bonino Pulejo24 enrolled

Overview

Comparison of two rehabilitation protocols in patients with Parkinson's disease and, therefore, identification of innovative rehabilitation protocols of proven and validated efficacy, through which it is possible to achieve: * Improved joint function and gait pattern * Reduction of the risk of falling or reduction of energy expenditure during physiological gait Evaluation of the increase in maximal effort tolerance · Improved cognitive performances Evaluation of the impact on the quality of life of the patient and family members Identification of morpho-functional markers predictive of clinical and rehabilitative out-come through neuroimaging study.

rehabilitation protocols in patients with Parkinson's disease and, therefore, identification of innovative rehabilitation protocols of proven and validated efficacy, through which it is possible to achieve: Improved joint function and gait pattern Reduction of the risk of falling or reduction of energy expenditure during physiological gait Evaluation of the increase in maximal effort tolerance · Improved cognitive performances Evaluation of the impact on the quality of life of the patient and family members Identification of morpho-functional markers predictive of clinical and rehabilitative out-come through neuroimaging study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Parkinson Disease

Interventions

IRMADEVICE

For patients in an advanced state of illness, advanced neuromotor rehabilitation treatment included 1) robot therapies, 2) specific water courses (e.g. walking pools, hydrokinesiotherapy pools, etc.), 3) advanced cognitive treatments (e.g. virtual reality courses); 4) augmentative immersive therapy in a virtual environment; 5) courses also dedicated to social reintegration and inclusive activities (theatre-therapy, art-therapy, dance-therapy, agro-therapy, etc.).

Eligibility

Sex: ALLMin age: 60 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Hoehn \& Yahr between 2.0 and 3.0; * No need for a walking aid; * Mini-Mental State Examination (MMSE) score \>24; * Effective dopaminergic pharmacological control; * Absence of other relevant neurological comorbidities; * Absence of postural deformities (and/or Pisa syndrome); * Absence of severe cardiological pathologies (exertional angina, severe decompensation). * Ability to travel to the rehabilitation treatment site independently or with support Exclusion Criteria: * presence of Deep Brain Stimulation (DBS); * presence of severe heart and/or lung disease; * presence of therapeutic regimen in the definition phase; * impaired joint and/or motor function to follow a proposed rehabilitation treatment programme * contraindications to performing MRI scans * undergoing rehabilitation therapy in the 3 months preceding enrolment.

Rehabilitation in Parkinson Disease Cyclone in Life

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes