Evaluation of Some Inflammatory Markers in Autism Spectrum Disorders

Overview

Evaluate some Inflammatory markers \[IL-6, IL-8, TNF\_alpha\] in children with autism spectrum disorder

several studies have suggested a correlation between ASD and abnormal immune activation (9) For instance, there is a high incidence of autistic subjects in families with other autoimmune disorders such as celiac disease and rheumatoid arthritis, suggesting a potential role for immune dysfunction in the pathophysiology of ASD High levels of IL-6 in the brain could determine alterations of synapse formation, dendritic spine development, and neuronal circuit balance \[13\], while in plasma they have been associated with increased stereotypical behaviors and with regressive forms of ASD

Conditions

Interventions

Eligibility

Outcomes

Central Contacts