Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma

Kunwu Yan,MM95 enrolled

Overview

Study of the relationship between hemodynamic stability and preoperative intravenous rehydration in patients with pheochromocytoma

All patients were subclassified into either the hemodynamic stability group (HS group) or the hemodynamic instability group (HU group) according to whether intraoperative hemodynamic instability occurred. Differences in data between the two groups were examined, and the risk factors for intraoperative hemodynamic instability were analyzed using logistic regression.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Adrenal Pheochromocytoma Hemodynamic

Interventions

Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytomaDRUG

Abandonment of intravenous volume expansion with alpha-blockers during preoperative preparation in patients with pheochromocytoma

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: Clinical diagnosis of adrenal pheochromocytoma Must be able to swallow tablets Exclusion Criteria: Bilateral or multiple pheochromocytomas. Ectopic pheochromocytoma

Outcomes

Primary Outcomes

intraoperative mean arterial pressure

an intraoperative mean arterial pressure \<60 mmHg is considered to be hemodynamically unstable

Time frame: During surgery

Data from ClinicalTrials.gov

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