Efficacy of Combined Scaffolds and Sodium Hypochlorite in Regenerative Endodontics of Immature Teeth

Overview

The aim of the study is to evaluate the efficacy of combinations of different scaffolds (blood clot, platelet rich fibrin, collagen) and sodium hypochlorite concentrations (0.5%- 2.5%) in regenerative endodontics of immature non-vital anterior teeth clinically and radiographically using cone-beam computed tomography.

Patients will be divided randomly into six equal groups (n=8) * Group I: BC scaffold and 0.5% concentration of NaOCl irrigant solution. * Group II: BC scaffold and 2.5% concentration of NaOCl irrigant solution. * Group III: PRF scaffold and 0.5% concentration of NaOCl irrigant solution. * Group IV: PRF scaffold and 2.5% concentration of NaOCl irrigant solution. * Group V: Collagen scaffold and 0.5% concentration of NaOCl irrigant solution. * Group VI: Collagen scaffold and 2.5% concentration of NaOCl irrigant solution. CBCT image will be obtained for baseline records after placement of the final resin restoration then the patients will be recalled after 6 months and 12 months for evaluating any changes in root length, root canal width, apex diameter and lesion size if present. The success rates for patients at each recall visit will be scored as follows 1. Score 0: Persistence of clinical and radiographic findings. 2. Score 1: Absence of swelling, drainage and pain along with radiographic evidence of osseous healing + no evidence of increased root dimensions. 3. Score 2: Absence of swelling, drainage and pain along with radiographic evidence of osseous healing + radiographic root development.

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Central Contacts