The purpose of this study is to assess the safety, tolerability, and single-dose pharmacokinetics of danicamtiv in healthy Japanese and Caucasian participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
33
Specified dose on specified days
Specified dose on specified days
Anaheim Clinical Trials
Anaheim, California, United States
Number of Participants with Adverse Events (AEs)
Time frame: Day 1 up to Day 28
Number of Participants with Vital Sign Abnormalities
Time frame: Day 1 up to Day 7
Number of Participants with Electrocardiogram (ECG) Abnormalities
Time frame: Day 1 up to Day 7
Number of Participants with Physical Examination Abnormalities
Time frame: Day 1 up to Day 7
Number of Participants with Clinical Laboratory Abnormalities
Time frame: Day 1 up to Day 7
Maximum Observed Plasma Concentration (Cmax)
Time frame: Predose and at multiple timepoints (Day 1 up to Day 6) after dosing
Time of Maximum Observed Plasma Concentration (Tmax)
Time frame: Predose and at multiple timepoints (Day 1 up to Day 6) after dosing
Area Under the Plasma Concentration-time Curve From Time Zero Extrapolated to Infinite Time [AUC(0-inf)]
Time frame: Predose and at multiple timepoints (Day 1 up to Day 6) after dosing
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