Assess bone quality in MS patients through TBS and evaluate the potential effects exerted by different drugs used in MS treatment, which may affect BMD and TBS in MS patients
Study Type
OBSERVATIONAL
Enrollment
300
After collecting anthropometric data, information on environmental factors and lifestyle (smoking, alcohol intake, physical activity, sun exposure, vitamin D supplementation, fish consumption) will be acquired through a questionnaire. The genetic and environmental aspects related to multiple sclerosis will also be studied. Disability status will be assessed through the Kurtzke Extended Disability Status Scale (EDSS). \[10\] All recruited patients will be administered the questionnaire (Multiple Sclerosis Quality of Life-54 (MSQOL-54) composed of 14 scales and 54 items. The scales investigate physical functions, limitations with respect to physical and emotional role, pain, emotional well-being, degree of energy, perceptions of one's health, social, cognitive and sexual functioning, distress, changes in health, satisfaction with sexual functioning and quality of life in general.
IRCCS Centro Neurolesi Bonino Pulejo
Messina, Italy
DXA scanner (Horizon© DXA System)
The DXA scanner (Horizon© DXA System) measures bone mineral content relative to bone area.
Time frame: 6 months
Bone Mineral Density
BMD will be measured in the lumbar spine (L2-L4) and in the right and left femoral neck and trochanter regions.
Time frame: 6 months
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