Treatment of Urethral Stricture With Urethral Drug Ball

Inclusion Criteria: * 1\. Age ≥ 18 and ≤ 85 years old, male patients; 2\. Urethral stricture was confirmed by transurethral angiography, and the length of stricture was less than 2 cm; 3\. Maximum urine flow rate (Qmax)\<15 ml/s; 4\. There are obvious symptoms of urinary tract stricture such as slow urine rheology, difficulty in urination and incomplete urination; 5\. International Prostate Symptom Score (IPSS) ≥ 13; 6\. The guide wire must be able to pass through the stenosis segment; 7\. Patients who can understand the purpose of the trial, voluntarily participate in and sign the informed consent form, can independently complete effective questionnaires, and are willing to conduct clinical follow-up according to the research requirements. Exclusion Criteria: * 1\. Patients with multiple stenotic lesions; 2\. Patients with a history of allergy to paclitaxel and contrast agents, or patients undergoing treatment with drugs that may antagonize paclitaxel; 3\. Patients who have undergone hypospadias repair, urethroplasty, stricture expansion or incision in the past 3 months; 4\. Urethral stricture caused by the following causes: bacterial urethritis, untreated gonorrhea, lichen sclerosus or dry glans obliterans; 5\. There are other diseases that can cause lower urinary tract symptoms, such as overactivity of bladder, neurogenic bladder dysfunction, etc; 6\. There are adverse factors for catheter insertion; 7\. Patients with artificial penis or urethral sphincter, or urethral or prostate stent; 8\. Patients who have been diagnosed with urethra cancer, bladder cancer cancer or prostate cancer, or who have experienced pelvic radiotherapy in the past 2 years; 9\. For patients with severe renal insufficiency, their serum creatinine is more than 2.5mg/dL or they are undergoing hemodialysis; 10\. Patients with severe lung disease, cardiovascular disease, coagulation dysfunction and contraindication of anesthesia; 11\. Patients with poor control of diabetes (hemoglobin A1c\>8.0%); 12\. Patients with active urinary stones in the past 6 months; 13\. Patients who are not suitable for direct vision internal urethrotomy; 14\. Patients with pregnancy preparation plan; 15\. Patients who are participating in clinical trials of other drugs or medical devices and have not reached their main endpoint; 16\. Patients who cannot participate in the clinical trial due to other reasons considered by the investigator.