A Prospective, Single-center, Single-blind, Randomized split-face, controlled trial will be conducted. The goal of this clinical trial is to evaluate the efficacy and satisfaction of the Skinceuticals skin care product (CE) for skin repair following fraxel laser treatment and explore the medical value of fraxel laser therapy combined with Skinceuticals skin care product
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
50
fraxel laser therapy combined with Skinceuticals skin care product(CE) and routine moisturizing and sun protection
fraxel laser therapy combined with routine moisturizing and sun protection
Change in erythema score
Scoring criteria: 0 (no erythema), 1 (mild erythema), 2 (moderate erythema), and 3 (severe erythema)
Time frame: at day 7 post-procedure
Change from baseline in erythema score
Scoring criteria: 0 (no erythema), 1 (mild erythema), 2 (moderate erythema), and 3 (severe erythema)
Time frame: days 1, 3, 5 post-procedure
Change from baseline in edema score
Score 0 - no edema, score 1 - mild edema, score 2 - moderate edema, score 3 - severe edema
Time frame: days 1, 3, 5 ,7 post-procedure
Change from baseline in Erythema Index (EI)
Time frame: days 1, 3, 5 ,7 post-procedure
Change from baseline in melanin index(MI) Change from baseline in melanin index(MI)
Time frame: days 1, 3, 5 ,7 post-procedure
Change from baseline in stratum corneum water content
Time frame: days 1, 3, 5 ,7 post-procedure
Change from baseline in transepidermal water loss
Time frame: days 1, 3, 5 ,7 post-procedure
Change from baseline in sebum rate
Time frame: days 1, 3, 5 ,7 post-procedure
Subjects overall satisfaction
Satisfaction ratings were classified as: very satisfied, satisfied, dissatisfied, very dissatisfied
Time frame: days 1, 3, 5 ,7 post-procedure
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