Subjects receive either CPL-01, positive control, or negative control after herniorrhaphy and are then followed.
Subjects pain and rescue medication use is assessed after having received either CPL-01, placebo, or ropivacaine HCl for several days after hernia repair surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
518
Local infiltration of study drug
Opioid rescue allowed by IV if requested
Acetaminophen rescue allowed if requested
Todd Bertoch
Salt Lake City, Utah, United States
Pain control
Area under the curve of the numeric rating score for pain with activity, where 0 is no pain and 10 is worst pain imaginable
Time frame: 72 hours
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Opioid rescue allowed by mouth if requested
Local infiltration of study drug
Local infiltration of study drug
Surgical hernia repair