The goal of this observational study is to assess the evolution of oxygen pressure and arterial waveform during supervised exercise therapy in patients with peripheral arterial disease. The main questions it aims to answer are: * can a significant increase in oxygen pressure be observed at 3 weeks? * can a significant increase of oxygen pressure or arterial waveform be observed at 3, 6 or 9 weeks?
Peripheral arterial disease (PAD) is a frequent pathology that affects more than 200 million people worldwide, more than 800,000 in France, and is mainly of atheromatous origin. The prevalence of this disease in France is estimated at 11% in people over 40 years of age, with an annual additional cost of €11,000 per patient. Supervised exercise therapy (SET) is the first-line treatment for intermittent claudication PAD for at least 3 months, although 15-20% of patients will not benefit from this therapy. Ankle-Brachial Index, the main diagnostic and monitoring tool for PAD, is not altered during SET. Transcutaneous oximetry (TcPO2) has been used for many years in the diagnosis of chronic permanent ischaemia, in the choice of amputation level and more recently in the diagnosis of proximal PAD. No studies have investigated the evolution and predictive value of exercise TcPO2 in this context of SET. The assessment of arterial Doppler waveform using an objective classification has also never been performed in the specific context of SET. . The goal of this observational study is to assess the evolution of oxygen pressure and arterial waveform during supervised exercise therapy in patients with peripheral arterial disease. The main questions it aims to answer are: * can a significant increase in oxygen pressure be observed at 3 weeks? * can a significant increase of oxygen pressure or arterial waveform be observed at 3, 6 or 9 weeks. The perspective is to predict the effectiveness of SET in terms of maximum walking distance.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SCREENING
Masking
NONE
Enrollment
36
External proxe fixed to the skin and ultrasound examination.
Supervised exercise therapy consists of three exercise sessions per week for 3 months, combining treadmill walking, lower limb muscle strengthening and stretching exercises. It is considered highly effective for people with leg pain related to peripheral arterial disease and has shown statistically significant improvements in maximum walking distance and quality of life parameters.
CHU Caen Normandie
Caen, Normandy, France
RECRUITINGEvolution of oximetry at 3 week from baseline
To describe the evolution of oximetry during SET at 3 weeks from baseline (TcPO2 leg value)
Time frame: at 3 weeks
Evolution of doppler waveform at 3 week from baseline
To describe the evolution of doppler waveform during SET at 3 weeks from baseline (SB hemodynamic classification)
Time frame: at 3 weeks
Evolution of doppler waveform at 6 week from baseline
To describe the evolution of doppler waveform during SET at 6 weeks from baseline (SB hemodynamic classification)
Time frame: 6 weeks
Evolution of doppler waveform at 9 week from baseline
To describe the evolution of doppler waveform during SET at 9 weeks from baseline (SB hemodynamic classification)
Time frame: 9 weeks
Evolution of doppler waveform at 12 week from baseline
To describe the evolution of doppler waveform during SET at 12 weeks from baseline (SB hemodynamic classification)
Time frame: 12 weeks
Evolution of oximetry at 6 week from baseline
To describe the evolution of oximetry during SET at 6 weeks from baseline (TcPO2 leg value)
Time frame: at 6 weeks
Evolution of oximetry at 9 week from baseline
To describe the evolution of oximetry during SET at 9 weeks from baseline (TcPO2 leg value)
Time frame: at 9 weeks
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Evolution of oximetry at 12 week from baseline
To describe the evolution of oximetry during SET at 12 weeks from baseline (TcPO2 leg value)
Time frame: at 12 weeks