Intensive care patients with established invasive intracranial neuromonitoring due to neurotrauma are subjected to a repeated non-invasive sonographic recording of the optic-nerve-sheath-diameter (ONSD). The recorded images are analyzed through a machine-learning-algorithm and an experienced ultrasound operator. Results are correlated to the parallel recorded intracranial pressure (ICP). The study aims to establish ONSD as a supplementary for raised ICP.
During the intensive care stay, patients with implemented invasive intracranial pressure monitoring will have sonographic recording of the optic nerve sheath (video clip) with a parallel recording of the underlying ICP. The obtained image material is then i) analyzed by a machine-learning algorithm and ii) manually by 2 blinded differently experienced examiners (expert, novice) with respect to the ONSD. For the manual procedure, three individual measurements are made for each eye and the mean value is determined. Subsequently, the measured values of the two examiners and the automated procedure are correlated with the ICP recorded during the sonographic examination.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
60
Ultrasound-based determination of the optic nerve sheath diameter
University Hospital Tuebingen
Tübingen, Baden-Wurttemberg, Germany
Sonographic monitoring of optic nerve sheath
Repeated ultrasound-based measurement of optic nerve sheath in millimeter (mm)
Time frame: Single measurement post-trauma up to day 10
Invasively measured intracranial pressure
Continuously recorded invasively (intra-parenchymal, intra-ventricular) determined intracranial pressure (mmHg)
Time frame: Continuously from time of admission up to day 10
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